Efxone Injection

Description

Efxone Injection uses

Efxone inj contains Ceftriaxone, a broad-spectrum antibiotic, that is commonly employed in medical practice for various purposes, including

Bacterial Infections

Efxone Injection is a broad-spectrum antibiotic effective against pneumonia, meningitis, urinary tract infections (UTIs), skin and soft tissue infections, intra-abdominal infections, bone and joint infections, pelvic inflammatory disease (PID), and septicemia (bloodstream infections).

Sexually transmitted disease(STIs)

Ceftriaxone is crucial for treating gonorrhoea, especially as antibiotic-resistant strains become more prevalent. It’s often used in combination therapy to ensure effective treatment and prevent further spread of the infection.

Surgical Prophylaxis

In surgical procedures, Efxone injection is administered before, during, or after surgery to prevent infections. A single dose before surgery helps reduce the risk of surgical site infections and other postoperative complications.

Bacterial Endocarditis

For Bacterial endocarditis, it is a part of the treatment regimen along with other antibiotics. It targets the bacteria responsible for the infection, helping prevent further damage to the heart’s inner lining or valves.

Otitis Media

In severe cases of middle ear infection (otitis media), it is used when standard antibiotics have failed. Its broad-spectrum activity makes it effective against a wide range of bacteria causing the infection, especially when complications such as hearing loss are a concern.

Efxone Injection uses in urdu

بیکٹیریل انفیکشن: یہ انجیکشن ایک وسیع اسپیکٹرم اینٹی بائیوٹک ہے جو نمونیا، گردن توڑ بخار، پیشاب کی نالی کے انفیکشن، جلد اور نرم بافتوں کے انفیکشن، انٹرا پیٹ کے انفیکشن، ہڈیوں اور جوڑوں کے انفیکشن، شرونیی سوزش کی بیماری، اور سیپٹیسیمیا (خون کے دھارے کے انفیکشن) کے خلاف موثر ہے۔
جنسی طور پر منتقل ہونے والی بیماری: سوزاک کے علاج کے لیے یہ بہت ضروری ہے، خاص طور پر جب اینٹی بائیوٹک مزاحم تناؤ زیادہ عام ہو جاتا ہے۔ مؤثر علاج کو یقینی بنانے اور انفیکشن کے مزید پھیلاؤ کو روکنے کے لیے یہ اکثر امتزاج تھراپی میں استعمال ہوتا ہے۔
سرجیکل پروفیلیکسس: جراحی کے طریقہ کار میں، یہ انجکشن انفیکشن کو روکنے کے لیے سرجری سے پہلے، دوران یا بعد میں لگایا جاتا ہے۔ سرجری سے پہلے ایک خوراک سرجیکل سائٹ کے انفیکشن اور دیگر پوسٹ آپریٹو پیچیدگیوں کے خطرے کو کم کرنے میں مدد کرتی ہے۔
بیکٹیریل اینڈو کارڈائٹس: بیکٹیریل اینڈو کارڈائٹس کے لیے، یہ دیگر اینٹی بائیوٹکس کے ساتھ علاج کے طریقہ کار کا ایک حصہ ہے۔ یہ انفیکشن کے لیے ذمہ دار بیکٹیریا کو نشانہ بناتا ہے، جو دل کی اندرونی استر یا والوز کو مزید نقصان پہنچنے سے روکنے میں مدد کرتا ہے۔
اوٹائٹس میڈیا: درمیانی کان کے انفیکشن (اوٹائٹس میڈیا) کی شدید صورتوں میں، اس کا استعمال اس وقت کیا جاتا ہے جب معیاری اینٹی بائیوٹکس ناکام ہو جائیں۔ اس کی وسیع اسپیکٹرم سرگرمی اسے انفیکشن کا باعث بننے والے بیکٹیریا کی ایک وسیع رینج کے خلاف موثر بناتی ہے، خاص طور پر جب سننے میں کمی جیسی پیچیدگیاں تشویش کا باعث ہوں۔

Dosage

The dosage of ceftriaxone can vary depending on the type and severity of the infection being treated, as well as the age, weight, and renal function of the patient. Here’s a general overview of dosages for some common indications:

For Adults

• For most infections: 1 to 2 grams once daily, intravenously. The dosage may be adjusted based on the severity of the infection.
• For severe infections like meningitis or hospital-acquired pneumonia: Higher doses may be needed, up to 2 to 4 grams once daily.
• Surgical prophylaxis: A single dose of 1 to 2 grams administered one hour before surgery.

For Children

• The dosage for children is usually based on body weight, typically ranging from 50 to 100 mg/kg/day, administered once daily or in divided doses every 12 to 24 hours.
• For meningitis or severe infections: Higher doses may be needed, up to 100 mg/kg/day.

Side effects

Some side effects of Efxone injection are:

1. Digestive Upset: Nausea, vomiting, diarrhoea, or abdominal pain.
2. Injection Site Reactions: Pain, swelling, or redness at the injection site.
3. Allergic Reactions: Rashes, swelling, or difficulty breathing.
4. Kidney and Liver Issues: Possible damage or elevated enzymes.
5. Blood Disorders: Anemia, low white blood cell count, or low platelet count.
6. Clostridium difficile Infection: Diarrhea or colitis.
7. Central Nervous System Effects: Headache, dizziness, or confusion.

Warnings

Before using it is essential to be aware of the following warnings associated with Efxone Injection:

• Pregnancy: Ceftriaxone may be safe during pregnancy for bacterial infections, but only take it if advised by your doctor.
• Lactation: While there’s no evidence of risk, caution is advised for lactating females. Consult your doctor before using ceftriaxone.
• Driving: Ceftriaxone can cause dizziness, impacting driving skills.
• Liver: Ceftriaxone may lead to liver swelling and elevated enzyme levels, potentially causing liver damage. Use with caution.
• Kidney: Use ceftriaxone cautiously if you have kidney issues, as it can increase the risk of kidney damage.
• Alcohol: No recognized interaction with alcohol, but consult your doctor before consuming alcohol while taking ceftriaxone.

Precautions

It is important to be aware of the following precautions while using this injection:

1. Renal and Hepatic Impairment: Patients with severe kidney or liver issues may be more sensitive to the drug. Use caution in these cases.
2. Hypersensitivity: Patients with non-severe hypersensitivity to other beta-lactam antibiotics should also be cautious with ceftriaxone.
3. Monitoring: During prolonged treatment, monitor full blood count regularly to ensure safety and effectiveness.

Contraindications

Efxone Injection is contraindicated in patients with hypersensitivity to beta-lactam drugs. It should not be used in premature newborns with less than 41 weeks postmenstrual age or in neonates over 41 weeks postmenstrual age who have jaundice, hypoalbuminemia, acidosis, or hyperbilirubinemia. Additionally, concomitant treatment with IV calcium in neonates over 41 weeks postmenstrual age is not recommended due to the risk of lung and urinary tract precipitation.

Price in Pakistan

Efxone injections are available for Rs 68 in Pakistan.