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Afdol tablet 10mg


Memantine hydrochloride, commonly known as Afdol, is used for Alzheimer’s disease therapy that targets glutamatergic neurotransmission dynamics to minimize the impact of elevated glutamate levels.


Afdol tablet 10mg:uses,side effects and price in Pakistan

Memantine hydrochloride, also known as Afdol, is a pharmacological intervention for Alzheimer’s disease treatment. It targets the complex dynamics of glutamatergic neurotransmission, contributing to the disease’s symptoms and progression. As a powerful antagonist at NMDA receptors, it aims to reduce the effects of high glutamate levels in the brain, providing personalized treatment for moderate-to-severe Alzheimer’s patients.

Generic Name: Memantine Hydrochloride

Mechanism of Action:

Memantine is a noncompetitive, voltage-dependent NMDA-receptor antagonist with a modest affinity. It inhibits the consequences of pathologically increased tonic glutamate levels, which can lead to neuronal dysfunction.


Some uses of the Afdol tablet 10mg are:

  • Patients with mild-to-severe Alzheimer’s disease are treated.
  • Inhibiting the consequences of pathologically high tonic glutamate levels in the brain.
  • Symptoms of Alzheimer’s disease, such as disorientation and memory loss, are alleviated.
  • Providing focused intervention in instances where glutamatergic neurotransmission dysfunction, particularly at NMDA receptors, is suspected.
  • Mitigating neuronal dysfunction induced by glutamate abnormalities.
  • A pharmaceutical strategy for dealing with the advancement of neurodegenerative dementia.
  • Relieving typical Alzheimer’s symptoms such as headaches and tiredness.
  • Improving cognitive impairment in Alzheimer’s disease patients.
  • Acting as a voltage-dependent, uncompetitive NMDA-receptor antagonist with modest affinity.
  • As part of a complete Alzheimer’s disease treatment approach.

Uses in Urdu:

  • ہلکے سے شدید الزائمر کی بیماری والے مریضوں کا علاج کیا جاتا ہے۔
  • دماغ میں پیتھولوجیکل طور پر اعلی ٹانک گلوٹامیٹ کی سطح کے نتائج کو روکنا۔
  • الزائمر کی بیماری کی علامات، جیسے کہ بے ترتیبی اور یادداشت کی کمی، کو دور کیا جاتا ہے۔
  • ایسی صورتوں میں فوکسڈ مداخلت فراہم کرنا جہاں گلوٹامیٹرجک نیورو ٹرانسمیشن ڈسفکشن، خاص طور پر NMDA ریسیپٹرز میں، مشتبہ ہو۔
  • گلوٹامیٹ اسامانیتاوں کی وجہ سے نیورونل dysfunction کو کم کرنا۔
  • نیوروڈیجینریٹو ڈیمنشیا کی ترقی سے نمٹنے کے لیے ایک فارماسیوٹیکل حکمت عملی۔
  • الزائمر کی عام علامات جیسے سر درد اور تھکاوٹ سے نجات۔
  • الزائمر کی بیماری کے مریضوں میں علمی خرابی کو بہتر بنانا۔
  • معمولی تعلق کے ساتھ وولٹیج پر منحصر، غیر مسابقتی NMDA-رسیپٹر مخالف کے طور پر کام کرنا۔
  • الزائمر کی بیماری کے مکمل علاج کے نقطہ نظر کے حصے کے طور پر۔

Side effects:

Some side effects of Afdol tablet 10mg are:

  • Headache
  • Sleepiness
  • Constipation
  • Elevated liver function test results
  • Dizziness
  • Disturbances in balance
  • Breathing difficulty
  • Blood pressure that is too high
  • Hypersensitivity to drugs


  • Concurrent use of NMDA-antagonists such as amantadine, ketamine, or dextromethorphan should be avoided.
  • Patients with recent myocardial infarction, congestive heart failure (NYHA III-IV), and uncontrolled hypertension have little data. Close monitoring is advised.
  • Alzheimer’s disease can affect driving performance, and patients should be informed about changes in responsiveness when driving or using machines.

Pregnancy Category:

Before taking any medication, always visit your doctor.


Afdol tablet 10mg are availabe for Rs 560 in Pakistan.



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Vendor Information

  • Store Name: Smart Enterprises
  • Vendor: Smart Enterprises
  • Address: Main Bus Stop Mradan Sawabi Road
    Baghicha Dheri
    Khyber Pakhtunkhwa
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