Afdol tablet 10mg

Description

Afdol tablet 10mg: uses, side effects and price in Pakistan

Memantine hydrochloride, also known as Afdol, is a pharmacological intervention for Alzheimer’s disease treatment. It targets the complex dynamics of glutamatergic neurotransmission, contributing to the disease’s symptoms and progression. As a powerful antagonist at NMDA receptors, it aims to reduce the effects of high glutamate levels in the brain, providing personalized treatment for moderate-to-severe Alzheimer’s patients.

Generic Name: Memantine Hydrochloride

Mechanism of Action:

Memantine is a noncompetitive, voltage-dependent NMDA-receptor antagonist with a modest affinity. It inhibits the consequences of pathologically increased tonic glutamate levels, which can lead to neuronal dysfunction.

Uses:

Some uses of the Afdol tablet 10mg are:

• Patients with mild-to-severe Alzheimer’s disease are treated.
• Inhibiting the consequences of pathologically high tonic glutamate levels in the brain.
• Symptoms of Alzheimer’s disease, such as disorientation and memory loss, are alleviated.
• Providing focused intervention in instances where glutamatergic neurotransmission dysfunction, particularly at NMDA receptors, is suspected.
• Mitigating neuronal dysfunction induced by glutamate abnormalities.
• A pharmaceutical strategy for dealing with the advancement of neurodegenerative dementia.
• Relieving typical Alzheimer’s symptoms such as headaches and tiredness.
• Improving cognitive impairment in Alzheimer’s disease patients.
• Acting as a voltage-dependent, uncompetitive NMDA-receptor antagonist with modest affinity.
• As part of a complete Alzheimer’s disease treatment approach.

Uses in Urdu:

• ہلکے سے شدید الزائمر کی بیماری والے مریضوں کا علاج کیا جاتا ہے۔
• دماغ میں پیتھولوجیکل طور پر اعلی ٹانک گلوٹامیٹ کی سطح کے نتائج کو روکنا۔
• الزائمر کی بیماری کی علامات، جیسے کہ بے ترتیبی اور یادداشت کی کمی، کو دور کیا جاتا ہے۔
• ایسی صورتوں میں فوکسڈ مداخلت فراہم کرنا جہاں گلوٹامیٹرجک نیورو ٹرانسمیشن ڈسفکشن، خاص طور پر NMDA ریسیپٹرز میں، مشتبہ ہو۔
• گلوٹامیٹ اسامانیتاوں کی وجہ سے نیورونل dysfunction کو کم کرنا۔
• نیوروڈیجینریٹو ڈیمنشیا کی ترقی سے نمٹنے کے لیے ایک فارماسیوٹیکل حکمت عملی۔
• الزائمر کی عام علامات جیسے سر درد اور تھکاوٹ سے نجات۔
• الزائمر کی بیماری کے مریضوں میں علمی خرابی کو بہتر بنانا۔
• معمولی تعلق کے ساتھ وولٹیج پر منحصر، غیر مسابقتی NMDA-رسیپٹر مخالف کے طور پر کام کرنا۔
• الزائمر کی بیماری کے مکمل علاج کے نقطہ نظر کے حصے کے طور پر۔

Side effects:

Some side effects of Afdol tablet 10mg are:

• Headache
• Sleepiness
• Constipation
• Elevated liver function test results
• Dizziness
• Disturbances in balance
• Breathing difficulty
• Blood pressure that is too high
• Hypersensitivity to drugs

Warnings:

• Concurrent use of NMDA antagonists such as amantadine, ketamine, or dextromethorphan should be avoided.
• Patients with recent myocardial infarction, congestive heart failure (NYHA III-IV), and uncontrolled hypertension have little data. Close monitoring is advised.
• Alzheimer’s disease can affect driving performance, and patients should be informed about changes in responsiveness when driving or using machines.

Pregnancy Category:

Before taking any medication, always visit your doctor.

Price:

Afdol tablets 10mg are available for Rs 560 in Pakistan.