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Uses, Benefits and Dosage of Calcium In Pregnancy

Uses, Benefits and Dosage of Calcium In Pregnancy

  • June 11, 2024
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Why Calcium is Essential During Pregnancy

Pregnancy is a critical time for both the mother and her developing baby. One of the key nutrients that play a vital role during this time is calcium. Calcium is not only important for the maintenance of strong bones and teeth, but it also contributes to the healthy development of the baby.

The developing fetus requires a significant amount of calcium for skeletal development, and if the mother’s intake is insufficient, her body may leach calcium from her bones to meet the baby’s needs, potentially leading to osteoporosis later in life. Therefore, ensuring an adequate intake of calcium through diet or supplements is crucial for both the mother’s and the baby’s health.

Benefits of Calcium During Pregnancy

Calcium supplementation during pregnancy offers a myriad of benefits. It aids in the development of the baby’s bones, teeth, muscles, and nerves. It also helps prevent maternal bone density loss, reduces the risk of preeclampsia, and supports proper blood clotting.

Uses of Calcium During Pregnancy

Calcium is a vital mineral for both the mother and the developing baby during pregnancy. It plays several crucial roles in maintaining health and supporting proper fetal development. Here are the key uses of calcium during pregnancy:

1. Bone Development

  • Fetal Bone Growth: Calcium is essential for the development of the baby’s bones and teeth. Adequate calcium intake helps in the formation of a strong skeletal structure.
  • Mother’s Bone Health: To meet the baby’s calcium needs, the body may draw calcium from the mother’s bones if dietary intake is insufficient, potentially weakening her bones. Sufficient calcium intake helps maintain the mother’s bone density and reduces the risk of osteoporosis later in life.

2. Dental Health

Calcium is crucial for the formation of the baby’s teeth, which begin developing in the second trimester. Ensuring enough calcium helps in the proper development of both primary and permanent teeth.

3. Cardiovascular Function

  • Heart Function: Calcium plays a role in maintaining normal heart rhythm and muscle function, including the heart muscle. Adequate calcium ensures proper cardiovascular function for both the mother and the baby.
  • Blood Clotting: Calcium is involved in the blood clotting process, which is essential during childbirth to prevent excessive bleeding.

4. Muscular Function

Calcium is necessary for muscle contractions, including the uterine muscles during labor. It also supports general muscle function and helps prevent muscle cramps and spasms, which can be common during pregnancy.

5. Nervous System Development

  • Neurotransmission: Calcium is involved in neurotransmitter release, which is critical for nerve function. Proper calcium levels support the development of the fetal nervous system and brain.
  • Reducing Hypertension Risk: Adequate calcium intake may help reduce the risk of pregnancy-induced hypertension and preeclampsia, conditions that can affect both maternal and fetal health.

6. Hormonal Regulation

Calcium helps regulate parathyroid hormone levels, which are important for maintaining calcium balance in the blood and bones. Proper regulation ensures the mother’s and baby’s bodies can efficiently utilize calcium.

7. Breastfeeding Preparation

Calcium is important for preparing the mother’s body for breastfeeding. It ensures that the mother’s milk will be rich in calcium, supporting the baby’s growth and development after birth.

How Much Calcium is Needed During Pregnancy

The recommended daily calcium intake during pregnancy is 1000 mg for women aged 19-50. This requirement increases to 1300 mg for pregnant and breastfeeding adolescents. Expectant mothers need to ensure they are meeting these daily requirements through a combination of dietary sources and supplementation.

Choosing the Right Calcium Supplement

During pregnancy, it’s essential for women to carefully consider the type of calcium supplements they use to support their and their baby’s health. Red algae calcium emerges as a superior choice due to its high absorption rate, which helps prevent constipation—a common concern during pregnancy.

Additionally, it’s crucial to consider complementary nutrients like vitamin D, magnesium, zinc, iron, and vitamin K2, which play vital roles in calcium absorption and utilization. Osteosun Plus Tablets offers a superior source of these essential minerals, ensuring optimal health and development for both you and your baby.

Understanding WHO Recommendations

For pregnant women in areas where calcium intake is low, the WHO recommends taking 1.5 to 2.0 grams of calcium supplements daily to lower the risk of pre-eclampsia. This updated advice aligns with the 2016 WHO guidelines on antenatal care and replaces the 2013 guideline on calcium supplementation during pregnancy.

Sources of calcium

The best sources of calcium during pregnancy include a combination of dietary intake and, if necessary, supplements. Here’s a detailed look at the options:

Dietary Sources

Dairy Products

  • Milk
  • Cheese
  • Yogurt

These are excellent sources of calcium and also provide additional nutrients like protein and vitamin D, which aid in calcium absorption.

Fortified Foods

⦁ Fortified plant-based milks (such as almond, soy, or oat milk)
⦁ Fortified orange juice
⦁ Fortified cereals

These products have added calcium and are good alternatives for those who are lactose intolerant or prefer non-dairy options.

Leafy Green Vegetables

  • Kale
  • Broccoli
  • Bok choy
  • Collard greens
  • Spinach (Note: While spinach is high in calcium, it also contains oxalates which can reduce calcium absorption)

Fish with Edible Bones

Sardines
Salmon (canned with bones)

These are excellent sources of calcium and also provide omega-3 fatty acids, which are beneficial during pregnancy.

Nuts and Seeds

  • Almonds
  • Chia seeds
  • Sesame seeds

These are not only good sources of calcium but also provide healthy fats and protein.

Calcium Supplements

If dietary intake is insufficient, calcium supplements can be considered. There are several forms of calcium supplements available, and it’s important to choose the right one:

Calcium Carbonate

Calcium carbonate is known for its high elemental calcium content, typically comprising 40% by weight. However, it’s important to note that calcium carbonate can lead to constipation, an undesirable side effect, especially during pregnancy.

To mitigate this, it’s recommended to take calcium carbonate supplements with food to enhance absorption and potentially reduce the likelihood of digestive discomfort.

Examples: Tums, Caltrate.

Calcium Citrate

Contains less elemental calcium (21% by weight) but is more easily absorbed than calcium carbonate and can be taken with or without food.A good option for those with lower stomach acid.
Examples: Citracal.

Calcium from red algae (organic source)

Calcium derived from red algae is becoming increasingly popular as a natural and effective calcium source, particularly during pregnancy.

Osteosun Plus Tablets provide an exceptional supply of these essential minerals, promoting the health and well-being of both you and your baby. Here are some benefits of using red algae as a calcium source:

Natural Source

Red algae calcium is a plant-based and natural source of calcium, often preferred by those looking for alternatives to animal-derived calcium or synthetic supplements.

Bioavailability

Calcium from red algae is highly bioavailable, meaning it is easily absorbed and utilized by the body. This is due to its unique mineral composition and porous structure.

Trace Minerals

In addition to calcium, red algae also contain other essential trace minerals such as magnesium, iron, and potassium, which support overall health and enhance calcium absorption.

Digestive Comfort

Red algae calcium is gentle on the stomach and is less likely to cause constipation compared to some other calcium supplements like calcium carbonate.

Sustainability

Harvesting red algae is considered environmentally sustainable, making it an eco-friendly choice for those concerned about the environmental impact of their supplements.

Tips for Taking Calcium

Divide dosages: Because the body absorbs calcium best in small amounts (500 mg or less at a time), it’s advisable to take smaller doses several times a day if you’re taking supplements.

Avoid interactions: Calcium can interfere with the absorption of other minerals such as iron and zinc. If you are also taking iron supplements, take them at different times of the day.

Vitamin D: Ensure adequate vitamin D intake, as it is essential for calcium absorption. This can be achieved through sunlight exposure, diet, or supplements if necessary.

Calcium Metabolism During Pregnancy

During pregnancy, the body undergoes numerous physiological changes to support both maternal health and fetal development. These changes have significant implications for calcium metabolism, ensuring that both the mother and the developing fetus have adequate calcium for their needs.

Physiological Changes Affecting Calcium Metabolism

Falling Albumin Levels

    • As pregnancy progresses, the level of albumin in the blood decreases. Albumin is a protein that binds calcium in the blood.
    • The reduction in albumin leads to a decrease in the total serum calcium levels, primarily affecting the albumin-bound fraction of calcium.

Expansion of Extracellular Fluid Volume

Pregnancy causes an expansion of the extracellular fluid volume, which also contributes to the reduction in total serum calcium levels.

Increased Renal Function

The renal function increases during pregnancy, leading to higher urinary excretion of calcium. Despite this, the body compensates to maintain adequate calcium levels.

Placental Calcium Transfer

The placenta actively transports calcium from the mother to the fetus, especially during the third trimester when fetal skeletal growth is at its peak.

Homeostatic Mechanisms Maintaining Calcium Levels

Calcitropic Hormones

    • Parathyroid Hormone (PTH): PTH helps regulate calcium levels by increasing calcium release from bones, reducing urinary calcium excretion, and enhancing calcium absorption in the intestines.
    • Calcitonin: Calcitonin helps lower blood calcium levels by inhibiting bone resorption.
    • 1,25-Dihydroxyvitamin D3 (1,25(OH)2D): This active form of vitamin D increases intestinal absorption of calcium and phosphorus, ensuring adequate levels for both mother and fetus.

Intestinal Calcium Absorption

There is a significant increase in intestinal calcium absorption during pregnancy, driven by elevated levels of 1,25(OH)2D. This increase helps meet the heightened calcium demands of the growing fetus.

Urinary Calcium Excretion

Despite the increased urinary excretion of calcium due to enhanced renal function, the body compensates through increased dietary calcium absorption and bone turnover.

Bone Turnover

Bone resorption and formation rates increase during pregnancy. This heightened bone turnover helps mobilize calcium stored in the maternal skeleton to ensure a sufficient supply for fetal development.

Fetal Calcium Accretion

  • The fetal skeleton contains approximately 20–30 grams of calcium at birth.
  • The majority of fetal skeletal growth and calcium accretion occurs from mid-pregnancy onward, with the highest rate of calcium transfer to the fetus happening during the third trimester.

Calcium Absorption During Pregnancy

During pregnancy, calcium absorption significantly increases to meet the heightened demands of both the mother and the fetus.

Increased Absorption Rates

Maternal Intake: The increase in calcium absorption is closely linked to maternal calcium intake. For example, women consuming an average of 1171 mg of calcium daily absorbed 57% in the second trimester and 72% in the third trimester.

Mechanism of Absorption

  • Vitamin D: The active form of vitamin D (1,25-dihydroxyvitamin D) plays a crucial role in calcium absorption. During pregnancy, maternal serum levels of 1,25(OH)2D double, enhancing calcium-binding protein synthesis, which facilitates increased intestinal calcium absorption.
  • Enzymatic Conversion: The increase in 1-a-hydroxylase activity and additional placental synthesis convert more 25-hydroxy vitamin D to its active form.

Role of Calcitropic Hormones

  • Parathyroid Hormone (PTH): PTH levels decrease to low-normal in the first trimester and rise to the high-normal range in the third trimester, reflecting increased calcium transfer to the fetus. PTH also boosts the renal synthesis of 1,25(OH)2D3 to meet gestational calcium needs.
  • Parathyroid Hormone-related Protein (PTHrP): PTHrP levels increase during pregnancy. Produced by mammary and fetal tissues, PTHrP stimulates placental calcium transport and protects the maternal skeleton from excessive bone resorption by enhancing intestinal and renal calcium absorption.

Calcitonin

Protective Role: Increased maternal calcitonin levels in early pregnancy help protect the maternal skeleton from PTH-induced resorption while allowing PTH’s beneficial effects on gut and kidney calcium handling to continue.

Challenges with Low Calcium Intake

Even with enhanced absorption mechanisms, women with chronically low calcium intake (<500 mg/day) may not meet both maternal and fetal calcium needs.

Excretion

During pregnancy, physiological changes lead to increased maternal calcium absorption, resulting in physiological hypercalciuria, or elevated levels of calcium in the urine. Interestingly, urinary calcium levels remain within normal limits during fasting but rise postprandially, correlating with the increased absorption of calcium. Studies have shown that urinary calcium excretion can increase by up to 43% from prepregnancy levels to the third trimester, partly due to the 50% rise in the glomerular filtration rate (GFR) during pregnancy.

Despite the increase in urinary calcium excretion, women with low dietary calcium intake (<500 mg/day) exhibit more tightly regulated urinary calcium levels. However, the rise in intestinal calcium absorption is not offset by the increase in urinary excretion, resulting in a net positive maternal calcium retention during pregnancy, ensuring sufficient calcium for both maternal and fetal needs.

Risks and Considerations

While calcium supplementation is generally safe, excessive intake can lead to side effects such as constipation, kidney stones, and interference with iron and zinc absorption. Pregnant women need to consult with their healthcare provider before starting any supplementation regimen.

Hypercalcemia in Pregnancy

Hypercalcemia, or high levels of calcium in the blood, is rare during pregnancy, with the most common cause being hyperparathyroidism. This condition can have significant impacts on both the mother and the fetus, often leading to adverse outcomes such as increased risk of abortions, severe intrauterine growth retardation, and stillbirth.

During pregnancy, parathyroid hormone (PTH) levels are typically low to mid-normal, but higher-than-normal levels alongside elevated calcium levels may suggest primary hyperparathyroidism.

Hypercalcemia often coincides with hypercalciuria, where urinary calcium levels exceed 250 mg/day due to increased intestinal absorption and glomerular filtration rate (GFR) during pregnancy.

Hypercalcemia and hypercalciuria can lead to complications such as renal insufficiency, vascular and soft tissue calcification, and kidney stones, posing additional risks to pregnant women’s health.

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